In goats, FOXL2 has been shown to be a direct transcriptional activator of the cyp19 gene via its ovarian-specific promoter 2 [ ]. Growth differentiation factor-9 is required during early ovarian folliculogenesis.
Modified from . By contrast, oocytes in animals that will become females continue to mature Uchida et al.
However, both genes contribute to the regulation of estrogenic responses and may thus influence sex differentiation. Advisor: Gemmell, Neil J. Expression of a vas::EGFP transgene in primordial germ cells of the zebrafish.
GATA factors are divided into two families based on expression patterns, structure, and function [ 90 ]. At 21 dpf zebrafish sex determination and differentiation in Alice Springs approximately 30 dpf testis development is initiated in males simultaneously with ovarian apoptosis.
Finding clues to the riddle of sex determination in zebrafish. PLoS Genet.
Devlin RH and Nagahama Y Sex determination and sex differentiation in fish: an overview of genetic, physiological, and environmental influences. Quantitative analysis of fushi tarazu factor 1 homolog messenger ribonucleic acids in the pituitary of salmon at different prespawning stages.
Published online Nov Inter-sex variation in synaptonemal complex lengths largely determine the different recombination rates in male and female germ cells. This suggests that the two promoters regulate ff1a in tissue specific manners and during different developmental stages rather than rendering them separate functions.
As a more direct test of the hypothesis, they experimentally manipulated the numbers of PGCs by injecting dilute amounts of antisense morpholino oligos MO targeting the germ cell-localized dead-end dnd mRNA into fertilized eggs, as reduction of dnd function leads to loss of PGCs Weidinger et al.
Another case of stock enhancement concerns the rainbow trout for recreational fisheries that results in a considerable number of hatchery fish released into the wild environment. Studies of zebrafish GATA factors have so far been associated with the development of organ systems other than the urogenital, but binding sites for GATA4 have been found in the cyp19 gene promoter [ 96 , 97 ] suggesting a role in regulating aromatase expression.
Dev Genes Evol. Expression of a vas::EGFP transgene in primordial germ cells of the zebrafish. FEBS J.